Oral squamous cell carcinoma with clear cell change: a rare case report

Clear-cell variant of oral squamous cell carcinoma is an extremely rare entity. change can be seen in any the neoplasms, but as pure form variant, it difficult to find head-and-neck SCC. We hereby present a case report 71-year-old male who presented with growth erythematous patches on lateral pharyngeal wall for past 3 months. Histopathologic examination showed nests, islands and sheets malignant cells vesicular nuclei abundant clear cytoplasm. Neoplastic constituting majority nests exhibited changes. Special stain was performed identify nature cells. periodic acid Schiff-diastase (PAS-D) positivity Immunohistochemical study using antibody pan-cytokeratin revealed diffuse tumor